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Thank you for visiting hhmi.org, please use a higher version of IE or other browsers such as Chrome and Firefox. Skip to main content Skip to navigation Skip to main content Skip to footer Janelia Research Campus Biointeractive Tangled Bank Studios UGP Home About Our Scientists Programs Education News Search Menu About About HHMI is a science philanthropy whose mission is to advance basic biomedical research and science education for the benefit of humanity. Overview History Leadership Governance Financials Careers Policies For Our Hosts Doing Business with HHMI Our Scientists Our Scientists HHMI supports people, rather than projects, because it’s individual scientists who break barriers to advance knowledge. Overview HHMI Investigators Janelia Scientists International Scientists HHMI Professors Nobel Laureates Browse All Scientists An Inside Look Programs Programs HHMI empowers exceptional scientists and students to pursue fundamental questions in basic science. Overview Open Competitions Biomedical Research Science Education Education Education HHMI believes every student and citizen can experience science in a meaningful way. Overview Science Education Programs BioInteractive Tangled Bank Studios Resources Order Educational Materials News News HHMI shares the latest on our research, education, and organizational news. HHMI News Research News Science Education News Institute News Search News Archive Press Room Janelia Research Campus Biointeractive Tangled Bank Studios HHMI - Howard Hughes Medical Institute At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. COVID-19 HHMI's Response » Research Aug 12 2020 A New Map Catalogs the Effects of Coronavirus Mutations Scientists have analyzed every possible mutation to one key part of the coronavirus. The data could help guide vaccine and drug development and hint at how the virus might spread. Science Education Jul 31 2020 HHMI Awards 45 Gilliam Fellowships to Support Diversity in Science The Howard Hughes Medical Institute has selected 45 doctoral students and their advisers to advance diversity and inclusion in the sciences. Research Jul 15 2020 Blood Test Could Reveal When Rheumatoid Arthritis Will Strike Scientists have identified a new type of cell that appears in the bloodstream of rheumatoid arthritis patients shortly before joint inflammation flares. Research Jul 08 2020 How to Precisely Edit Mitochondrial DNA A gene editing tool based on a bacterial toxin can make precise changes to mitochondrial DNA inside cells. Research Jul 01 2020 New Way to See RNA Could Help Fight Pathogens Scientists have found a new way to identify genetic modifications to transfer RNAs that could be important in a wide variety of diseases. Research Jun 24 2020 Why Men May Fare Worse than Women Against SARS-CoV-2 Data from COVID-19 cases around the world suggest that the new coronavirus hits men harder than women. Differences in men and women’s immune responses to the virus may help explain why. Research Jun 18 2020 Fighting the COVID-19 Pandemic Through Testing Research labs are racing to develop innovative testing methods and overcome the bottlenecks to more widespread testing, which is crucial to controlling the spread of the disease. Research Jun 17 2020 Tomato’s Hidden Mutations Revealed in Study of 100 Varieties A new analysis of difficult-to-access genetic variation is the most comprehensive ever conducted in plants. It could guide the improvement of tomatoes and other crops. Research Jun 12 2020 Precision Genome Editing Enters the Modern Era CRISPR has sparked a renaissance in genome editing. Now, next-generation CRISPR technologies let scientists modify the genome more efficiently and more precisely than before. Such tools could one day serve as therapeutics, but many challenges remain. Research May 20 2020 Preventing ‘Cytokine Storm’ May Ease Severe COVID-19 Symptoms A clinical trial in people with the new coronavirus is testing a drug that may halt an overactive immune response before it ramps up. Research May 14 2020 Discovery of Malaria Parasite’s Clock Could Pave Way to New Treatments The parasite that causes malaria has its own internal clock, explaining the disease’s rhythmic fevers and opening new pathways for therapeutics. Research May 11 2020 SARS-CoV-2 Targets Many Cell Types, Analysis of Single-Cell Data Suggests The new coronavirus invades cells that sport certain molecules on their surfaces. A network of researchers realized they already had the data to identify these cells. Research May 01 2020 Molecular Basis of Rare Neurological Disorder Reveals Potential Treatment Edwin Chapman has long studied how one protein triggers the release of neurotransmitters, allowing neurons to communicate. A mother’s email prompted him to investigate what happens when this protein malfunctions. Institute Apr 30 2020 Clayton S. Rose Elected Chair of HHMI’s Trustees Clayton S. Rose, President of Bowdoin College and a longtime Howard Hughes Medical Institute Trustee, will succeed Kurt L. Schmoke as Chair of the Trustees. Research Apr 24 2020 Tracking the COVID-19 Pandemic with an App Researchers and a volunteer team from Pinterest developed How We Feel, an app that lets users report symptoms of the disease caused by the novel coronavirus. Research Apr 15 2020 A Gut-to-Brain Circuit Drives Sugar Preference and May Explain Sugar Cravings The sensation of sweetness starts on the tongue, but sugar molecules also trip sensors in the gut that directly signal the brain. This could explain why artificial sweeteners fail to satisfy the insatiable craving for sugar. Research Apr 07 2020 Repurposing Existing Drugs Could Offer Faster Path to COVID-19 Treatment A map of interactions between the novel coronavirus and human proteins is helping scientists identify drugs that might work as therapeutics. Research Mar 31 2020 Virus-Scanning Tool Could Detect Previous COVID-19 Infections and Inform Vaccine Development Using a research assay called VirScan, scientists plan to study how antibodies from people who have had COVID-19 attack the virus that causes it. Research Mar 26 2020 Citizen Scientists Are Helping Researchers Design New Drugs to Combat COVID-19 Using a free computer game called Foldit, researchers are enlisting the help of citizen scientists to design drugs that could stop the novel coronavirus from infecting human cells. Research Mar 24 2020 Patients with Severe Forms of Coronavirus Disease Could Offer Clues to Treatment A new international project aims to enroll 500 COVID-19 patients to search for genetic mutations that make some people more vulnerable to severe infection. Research Mar 05 2020 Resurrecting Ancient Protein Partners Reveals Origin of Protein Regulation After reconstructing the ancient forms of two cellular proteins, scientists discovered the earliest known instance of a complex form of protein regulation. Research Feb 06 2020 Fat Droplets Play Surprise Role in Metabolism Cellular structures once thought to be inactive fat storage centers may actually help regulate metabolism. Research Jan 30 2020 Uncovering the Neural Basis for Hypothetical Thinking in Rats As a rat approaches a maze juncture, neural activity rapidly cycles between two sets of cells. The discovery suggests the rodents are envisioning turning left or right. A similar phenomenon may underlie how humans make decisions. Research Jan 22 2020 Unveiling the Biggest and Most Detailed Map of the Fly Brain Yet Janelia and Google scientists have constructed the most complete map of the fly brain ever created, pinpointing millions of connections between 25,000 neurons. Now, a wiring diagram of the entire brain is within reach. Load More Research Aug 12 2020 A New Map Catalogs the Effects of Coronavirus Mutations Scientists have analyzed every possible mutation to one key part of t...